Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | S100B | P04271 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11291824 | 0.98 | MAPT (0.51) | MAPTGAAPOLBCNR2CNR1 | |
| SCHEMBL11131815 | 0.88 | MAPT (0.51) | MAPTCNR2CNR1CYP3A4HTT | |
| SCHEMBL23337438 | 0.85 | MAPT (0.55) | MAPTGAAPOLBCYP3A4ALOX15 | |
| SCHEMBL11290937 | 0.84 | KMT2A (0.45) | MAPTCYP3A4HTT | |
| SCHEMBL11295078 | 0.84 | MAPT (0.51) | MAPTGAACNR2CNR1CYP3A4 | |
| SCHEMBL11306234 | 0.83 | MAPT (0.53) | MAPTGAAPOLBCYP3A4ALOX15 | |
| SCHEMBL11710855 | 0.83 | AKR1C2 (0.61) | MAPTCNR2CNR1BCL2MCL1 | |
| SCHEMBL5962843 | 0.83 | MEN1 (0.56) | MAPTGAACNR2CNR1ALOX15 | |
| SCHEMBL8508473 | 0.82 | MAPT (0.51) | MAPTGAAPOLBCNR2CNR1 | |
| SCHEMBL31000389 | 0.81 | RECQL (0.67) | MAPTGAAPOLBALOX15S100B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | claimed |
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |