Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11131815 | 0.89 | MAPT (0.51) | MAPTCNR1CNR2LMNAHTT | |
| SCHEMBL11288483 | 0.85 | MAPT (0.55) | MAPTL3MBTL1ALDH1A1GAALMNA | |
| SCHEMBL11290937 | 0.84 | KMT2A (0.45) | MAPTLMNAHTTKMT2AMEN1 | |
| SCHEMBL11291087 | 0.84 | MAPT (0.48) | MAPTL3MBTL1ALDH1A1GAALMNA | |
| SCHEMBL11293046 | 0.84 | MAPT (0.53) | MAPTCNR1CNR2ALDH1A1GAA | |
| SCHEMBL11311902 | 0.84 | CNR2 (0.53) | MAPTCNR1CNR2ALDH1A1GAA | |
| SCHEMBL11291383 | 0.84 | ABL1 (0.51) | MAPTL3MBTL1ALDH1A1GAALMNA | |
| SCHEMBL11294900 | 0.84 | MAPT (0.57) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL11296989 | 0.83 | LMNA (0.51) | MAPTALDH1A1LMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11291824 | 0.83 | MAPT (0.51) | MAPTCNR1CNR2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |