Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398951 | 0.90 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2G6PD | |
| SCHEMBL11295096 | 0.89 | NPC1 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2G6PD | |
| SCHEMBL11294057 | 0.89 | KMT2A (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2G6PD | |
| SCHEMBL11356315 | 0.84 | SMN1; SMN2 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2G6PD | |
| SCHEMBL11393669 | 0.84 | MAPT (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2G6PD | |
| SCHEMBL11361043 | 0.84 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2G6PD | |
| SCHEMBL11293028 | 0.83 | NPC1 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11214313 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2G6PD | |
| SCHEMBL11296286 | 0.80 | NPC1 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2G6PD | |
| SCHEMBL11403264 | 0.80 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252961-A | Intermediates of and process for making 3-[5-[1-(2-, 3-, or 4-methyl, or ethyl or isopropylphenoxy)alkyl, alkynyl, alkenyl, or haloalkyl]-1,3,4-thiadiazol-2-yl]-4-hydroxy-1-methyl-2-imidazolidinones | PPG INDUSTRIES, INC. (US) | 1981-02-24 | — | — | US | disclosed |
| US-4218236-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | PPG INDUSTRIES, INC. (US) | 1980-08-19 | — | — | US | disclosed |