Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293787 | 0.96 | TAAR1 (0.48) | TAAR1NPC1RAB9AMEN1LMNA | |
| SCHEMBL11292830 | 0.92 | TAAR1 (0.49) | TAAR1NPC1RAB9AHTR1AALOX5 | |
| SCHEMBL11292832 | 0.92 | TAAR1 (0.49) | TAAR1NPC1RAB9AHTR1AALOX5 | |
| SCHEMBL11293747 | 0.85 | TAAR1 (0.46) | TAAR1NPC1RAB9ALMNAKMT2A | |
| SCHEMBL11293744 | 0.85 | TAAR1 (0.46) | TAAR1NPC1RAB9ALMNAKMT2A | |
| SCHEMBL11288890 | 0.82 | TAAR1 (0.51) | TAAR1NPC1RAB9AHTR1AALOX5 | |
| SCHEMBL11288889 | 0.82 | TAAR1 (0.51) | TAAR1NPC1RAB9AHTR1AALOX5 | |
| SCHEMBL11303561 | 0.81 | TAAR1 (0.43) | TAAR1HTR1A | |
| SCHEMBL11303559 | 0.81 | TAAR1 (0.43) | TAAR1HTR1A | |
| SCHEMBL11296641 | 0.81 | TAAR1 (0.47) | TAAR1NPC1RAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064820-A1 | Substituted imidazole and imidazoline derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-11-17 | — | — | EP | disclosed |