Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288890 | 1.00 | TAAR1 (0.51) | TAAR1NPC1RAB9AHTR1AACP1 | |
| SCHEMBL11292830 | 0.85 | TAAR1 (0.49) | TAAR1NPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL11292832 | 0.85 | TAAR1 (0.49) | TAAR1NPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL11298150 | 0.84 | TAAR1 (0.41) | TAAR1NPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL11293787 | 0.84 | TAAR1 (0.48) | TAAR1NPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL11293809 | 0.82 | TAAR1 (0.47) | TAAR1NPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL11294169 | 0.81 | TAAR1 (0.51) | TAAR1NPC1RAB9AHTR1AACP1 | |
| SCHEMBL11294167 | 0.81 | TAAR1 (0.51) | TAAR1NPC1RAB9AHTR1AACP1 | |
| SCHEMBL11299731 | 0.77 | TAAR1 (0.45) | TAAR1NPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL11299729 | 0.77 | TAAR1 (0.45) | TAAR1NPC1RAB9AHTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064820-A1 | Substituted imidazole and imidazoline derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-11-17 | — | — | EP | disclosed |