SCHEMBL11294014

SCHEMBL11294014

CCOC(=O)C1(C(C)C)CCCC1=O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 8/20 0.55
CYP3A4 P08684 6/20 0.55
TSHR P16473 4/20 0.50
CYP2C9 P11712 3/20 0.50
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
CYP2D6 P10635 1/20 0.49
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
ATM Q13315 1/20 0.36
F10 P00742 1/20 0.33
OPRM1 P35372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8980509 0.81 CYP2C19 (0.51) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1
SCHEMBL10817859 0.80 CYP2C19 (0.46) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1
SCHEMBL11102551 0.79 CYP2C19 (0.39) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1
SCHEMBL8567194 0.78 CYP2C19 (0.45) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1
SCHEMBL28255942 0.77 CYP2C19 (0.45) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1
SCHEMBL14338559 0.77 CYP2C19 (0.44) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1
SCHEMBL27794018 0.77 CYP2C19 (0.67) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1
SCHEMBL11635765 0.76 CYP2C19 (0.36) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1
SCHEMBL4812294 0.75 CYP2C19 (0.42) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1
SCHEMBL7053478 0.75 CYP2C19 (0.43) CYP2C19CYP3A4TSHRCYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100348571-C 2-alkoxyl cyclopentyl ester compound, its synthesis method and application CHINA PETROLEUM & CHEMICAL (CN) 2007-11-14 CN disclosed
CN-1789234-A 2-alkoxyl cyclopentyl ester compound, its synthesis method and application CHINA PETROLEUM & CHEMICAL (CN) 2006-06-21 CN disclosed
CN-1247508-C Ether kind compound containing cyclopentyl and its synthesis method and application CHINA PETROCHEMICAL CORP (CN) 2006-03-29 CN disclosed
CN-1597650-A Ether kind compound containing cyclopentyl and its synthesis method and application CHINA PETROCHEMICAL CORP (CN) 2005-03-23 CN disclosed
US-4318900-A STIMULANTS WILKINSON SWORD LIMITED (GB) 1982-03-09 US disclosed
US-4248859-A USED IN EDIBLE AND TOPICAL PREPARATIONS WILKINSON SWORD LIMITED (GB) 1981-02-03 US disclosed