Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 10/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294014 | 0.81 | CYP2C19 (0.55) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL14338558 | 0.78 | CYP2C19 (0.43) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL3670181 | 0.74 | CYP2C19 (0.41) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL16451038 | 0.73 | CYP2C19 (0.37) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL1009636 | 0.73 | CYP2C19 (0.40) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL12083378 | 0.72 | CYP2C19 (0.39) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL5352623 | 0.72 | EED (0.42) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL10046851 | 0.72 | EED (0.42) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL14625084 | 0.72 | CYP2C9 (0.82) | CYP2C19TSHRCYP3A4MAPTCYP2C9 | |
| SCHEMBL9583303 | 0.70 | TSHR (0.39) | CYP2C19TSHRCYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712836-A1 | Alkyl 3-benzylidene-1-alkyl-2-oxocyclopentanecarboxylate derivates as fungicides | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |
| US-5519160-A | FUNGICIDES | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |