Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A known ✓ | P35498 | 1/20 | 0.51 |
| ▸ | SCN2A known ✓ | Q99250 | 1/20 | 0.51 |
| ▸ | SCN3A known ✓ | Q9NY46 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121361 | 0.92 | MAPT (0.85) | MAPTCA1CA2CA4CA7 | |
| SCHEMBL14914 | 0.92 | MAPT (0.85) | MAPTCA1CA2CA4CA7 | |
| Bromide SCHEMBL27974437 | 0.90 | MAPT (0.82) | MAPTCA1CA2CA4CA7 | |
| SCHEMBL587369 | 0.90 | MAPT (0.82) | MAPTCA1CA2CA4CA7 | |
| Methane SCHEMBL28009609 | 0.90 | MAPT (0.82) | MAPTCA1CA2CA4CA7 | |
| SCHEMBL28996270 | 0.90 | MAPT (0.82) | MAPTCA1CA2CA4CA7 | |
| SCHEMBL8849064 | 0.90 | MAPT (0.82) | MAPTCA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL28406796 | 0.90 | MAPT (0.82) | MAPTCA1CA2CA4CA7 | |
| Potassium SCHEMBL30309050 | 0.90 | MAPT (0.82) | MAPTCA1CA2CA4CA7 | |
| Water SCHEMBL28419344 | 0.89 | MAPT (0.79) | MAPTCA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012944-B1 | COLOUR-FAST MONOAZO PIGMENT MIXTURES STABLE AGAINST RECRYSTALLISATION, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-23 | — | — | EP | disclosed |
| EP-0012944-A1 | Colour-fast monoazo pigment mixtures stable against recrystallisation, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-07-09 | — | — | EP | disclosed |