SCHEMBL1129446

SCHEMBL1129446

Cc1cc(C(C)(C)c2ccccc2)cc(C(=O)O)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
HMGB1 P09429 1/20 0.49
CXCL12 P48061 1/20 0.49
KDM4E B2RXH2 1/20 0.49
ESR1 P03372 3/20 0.47
ESR2 Q92731 3/20 0.47
CYP3A4 P08684 2/20 0.47
KMT2A Q03164 2/20 0.46
CYP2C9 P11712 2/20 0.46
CNR1 P21554 3/20 0.44
CNR2 P34972 3/20 0.44
THRB P10828 2/20 0.43
MEN1 O00255 1/20 0.43
PSMD14 O00487 1/20 0.43
HSP90AA1 P07900 1/20 0.43
MMP2 P08253 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7087887 0.98 HMGB1 (0.47) ALDH1A1HPGDHSD17B10HMGB1CXCL12
SCHEMBL10462619 0.91 HMGB1 (0.56) ALDH1A1HPGDHSD17B10HMGB1CXCL12
SCHEMBL11753846 0.87 CNR1 (0.50) ALDH1A1HPGDHSD17B10HMGB1CXCL12
Zinc Ion SCHEMBL7087886 0.86 ESR1 (0.43) ALDH1A1HPGDHSD17B10HMGB1CXCL12
SCHEMBL1129729 0.85 ESR1 (0.46) ALDH1A1HPGDHSD17B10HMGB1CXCL12
SCHEMBL11474791 0.85 HPGD (0.50) ALDH1A1HPGDHSD17B10HMGB1CXCL12
SCHEMBL1129780 0.84 AKR1C2 (0.55) ALDH1A1HPGDHSD17B10KDM4EESR1
Water SCHEMBL9852464 0.84 ESR1 (0.44) ALDH1A1HPGDHSD17B10HMGB1CXCL12
SCHEMBL9615386 0.84 NR5A2 (0.48) ALDH1A1HPGDHSD17B10KDM4EESR1
SCHEMBL5072689 0.84 ESR1 (0.62) ALDH1A1HPGDHSD17B10HMGB1CXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 EP disclosed
US-7235512-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-06-26 US disclosed
US-7176162-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-02-13 US disclosed
EP-1348569-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 2006-10-04 EP disclosed
EP-1291196-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 2006-06-21 EP disclosed
US-6986979-B2 Microcapsule composition EASTMAN KODAK COMPANY (US) 2006-01-17 US disclosed
WO-2005073805-A2 COMPOSITION COMPRISING MICROCAPSULES EASTMAN KODAK COMPANY (US) 2005-08-11 WO disclosed
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
US-4920091-A CONTAINING SALICYLIC ACID DERIVATIVE AS ELECTRON ACCEPTING COLOR DEVELOPER; STABLE IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1990-04-24 US disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed
US-4808566-A COLORLESS DYE IS DIMER OF 3-(4-SUBSTITUTED AMINOARYL)-3-(SUBSTITUTED INDOL-3-YL) PHTHALIDE FUJI PHOTO FILM CO., LTD. (JP) 1989-02-28 US disclosed
EP-0262810-A2 Sheet recording material containing dye-forming components Fuji Photo Film Co., Ltd. (JP) 1988-04-06 EP disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed