SCHEMBL11474791

SCHEMBL11474791

Cc1cc(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc(C(=O)O)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.50
HSD17B10 Q99714 3/20 0.50
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 2/20 0.50
HMGB1 P09429 2/20 0.50
CXCL12 P48061 2/20 0.50
KMT2A Q03164 3/20 0.47
CYP2C9 P11712 2/20 0.47
CYP3A4 P08684 1/20 0.47
THRB P10828 2/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
PSMD14 O00487 1/20 0.44
HSP90AA1 P07900 1/20 0.44
MMP2 P08253 1/20 0.44
GAA P10253 1/20 0.44
MAPK1 P28482 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL11475567 0.85 ALDH1A1 (0.39) HPGDHSD17B10ALDH1A1KDM4EHMGB1
SCHEMBL1129446 0.85 ALDH1A1 (0.49) HPGDHSD17B10ALDH1A1KDM4EHMGB1
SCHEMBL7087887 0.83 HMGB1 (0.47) HPGDHSD17B10ALDH1A1KDM4EHMGB1
SCHEMBL4601584 0.83 PTGS1 (0.50) ALDH1A1KMT2ACYP2C9CYP3A4MEN1
SCHEMBL3807152 0.82 HMGB1 (0.56) HPGDHSD17B10ALDH1A1KDM4EHMGB1
SCHEMBL11671062 0.81 ESR1 (0.50) ALDH1A1KMT2ACYP2C9CYP3A4MEN1
SCHEMBL10943232 0.80 HMGB1 (0.55) HPGDHSD17B10ALDH1A1KDM4EHMGB1
SCHEMBL9652212 0.80 HMGB1 (0.47) HPGDHSD17B10ALDH1A1KDM4EHMGB1
SCHEMBL10462619 0.78 HMGB1 (0.56) HPGDHSD17B10ALDH1A1KDM4EHMGB1
SCHEMBL11475507 0.76 CSNK2A1 (0.59) HPGDALDH1A1KDM4EHMGB1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4219219-A Developers for pressure-sensitive recording and developing sheets containing them FUJI PHOTO FILM CO., LTD. (JP) 1980-08-26 US disclosed