SCHEMBL1129468

SCHEMBL1129468

CC(c1ccccc1)c1ccc(-c2ccccc2)c(C(=O)O)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.44
PTGS1 P23219 3/20 0.39
PTGS2 P35354 3/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
AKR1C3 P42330 2/20 0.39
AKR1C2 P52895 2/20 0.39
AKR1C1 Q04828 2/20 0.39
FABP2 P12104 1/20 0.39
TSHR P16473 1/20 0.39
AKR1C4 P17516 1/20 0.39
ADRA2B P18089 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2C P28335 1/20 0.39
DRD3 P35462 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10487156 0.84 TYR (0.49) TYRLMNAHPGDPTGESALOX5
SCHEMBL1129856 0.81 TYR (0.46) TYRKMT2AMEN1TSHRCYP1A2
SCHEMBL9497285 0.80 TYR (0.45) TYRKMT2AMEN1TSHRCYP1A2
SCHEMBL11758949 0.79 TYR (0.50) TYRPTGS1PTGS2TSHRLMNA
SCHEMBL29002025 0.79 TYR (0.44) TYRKMT2AMEN1LMNAPTGES
SCHEMBL8369077 0.77 TYR (0.42) TYRPTGS1PTGS2KMT2AMEN1
Zinc Ion SCHEMBL10487151 0.75 TYR (0.46) TYRKMT2AMEN1LMNAHPGD
SCHEMBL8369817 0.74 TYR (0.40) TYRPTGS1PTGS2KMT2AMEN1
SCHEMBL9615366 0.74 TYR (0.45) TYRTSHRLMNAP2RX3
SCHEMBL9312394 0.74 DPP4 (0.53) TYRKMT2AMEN1AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 EP disclosed
EP-0338808-B1 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INT INC (US) 1995-08-23 EP disclosed
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 EP disclosed
US-5187143-A Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-02-16 US disclosed
EP-0482668-A1 Heat sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-04-29 EP disclosed
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
US-4920091-A CONTAINING SALICYLIC ACID DERIVATIVE AS ELECTRON ACCEPTING COLOR DEVELOPER; STABLE IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1990-04-24 US disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed