SCHEMBL9615366

SCHEMBL9615366

Cc1c(C(C)c2ccccc2)cc(C(C)c2ccccc2)c(O)c1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.45
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
P2RX3 P56373 1/20 0.40
FABP3 P05413 1/20 0.39
FABP4 P15090 1/20 0.39
LDHA P00338 7/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
LDHB P07195 6/20 0.37
ALB P02768 1/20 0.37
GRM1 Q13255 1/20 0.36
VKORC1 Q9BQB6 1/20 0.35
DHODH Q02127 1/20 0.35
PDE10A Q9Y233 1/20 0.35
RXRA P19793 1/20 0.35
BRD4 O60885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11758949 0.90 TYR (0.50) TYRGAATSHRHTTNPSR1
SCHEMBL11759213 0.80 TYR (0.47) TYRGAATSHRHTTNPSR1
SCHEMBL1129856 0.79 TYR (0.46) TYRGAATSHRHTTNPSR1
SCHEMBL10487156 0.79 TYR (0.49) TYRP2RX3FABP3FABP4GABRA1
SCHEMBL9497285 0.78 TYR (0.45) TYRGAATSHRHTTNPSR1
SCHEMBL7782911 0.75 TYR (0.45) TYRGAATSHRHTTNPSR1
SCHEMBL8365915 0.75 TYR (0.42) TYRGAATSHRHTTNPSR1
SCHEMBL224197 0.74 TYR (0.55) TYRGAATSHRHTTNPSR1
SCHEMBL29002025 0.74 TYR (0.44) TYRGAAHTTP2RX3FABP3
SCHEMBL1129468 0.74 TYR (0.44) TYRTSHRP2RX3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128309-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1992-07-07 US disclosed