Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798822 | 0.87 | PDE7A (0.47) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10024451 | 0.84 | PDE7A (0.40) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10024498 | 0.80 | PDE7A (0.42) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11202237 | 0.78 | PDE7A (0.49) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11297209 | 0.78 | MAPT (0.49) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL11292807 | 0.78 | MAPT (0.49) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL18614898 | 0.78 | PDE7A (0.51) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7293896 | 0.78 | PDE7A (0.51) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3386571 | 0.78 | MEN1 (0.53) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8610040 | 0.77 | KDM4E (0.52) | PDE7ASMN1; SMN2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342859-A | Bis(aminophenylthioalkyl)terephthalate and hardener for polyurethane elastomer thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-08-03 | — | — | US | disclosed |