Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KIF11 | P52732 | 6/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003176 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1MAPTKIF11PDE7A | |
| SCHEMBL8904293 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1MAPTKIF11PDE7A | |
| SCHEMBL10970030 | 0.85 | MAPT (0.49) | KDM4EALDH1A1MAPTPDE7ASMN1; SMN2 | |
| SCHEMBL7979177 | 0.85 | SLC6A2 (0.51) | KDM4EALDH1A1MAPTPDE7ASMN1; SMN2 | |
| SCHEMBL9064821 | 0.84 | GRM8 (0.49) | KDM4EALDH1A1MAPTKIF11GRM8 | |
| SCHEMBL25180568 | 0.82 | KIF11 (0.42) | KDM4EALDH1A1MAPTKIF11 | |
| SCHEMBL25180569 | 0.82 | KIF11 (0.42) | KDM4EALDH1A1MAPTKIF11 | |
| SCHEMBL8964242 | 0.82 | MAPT (0.61) | ALDH1A1MAPTGRM8GRM4GAA | |
| SCHEMBL8963352 | 0.82 | MAPT (0.61) | ALDH1A1MAPTGRM8GRM4GAA | |
| SCHEMBL30377087 | 0.81 | CYP1A2 (0.50) | KDM4EALDH1A1MAPTPDE7ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824663-A | MALODOR FORMING ENZYME ACTS ON A SERINE ETHER TO RELEASE ODORLESS COMPOUND OR COMPOUND WITH PLEASANT ODOR RATHER THAN ACTING ON APOCRINE SECRETIONS TO PRODUCE MALODOR | THE GILLETTE COMPANY (US) | 1998-10-20 | — | — | US | disclosed |
| US-5514671-A | SERINE ALKYL, CYCLOHEXYL OR AROMATIC ETHERS IN VEHICLE; SUPPRESSING BODY ODOR BY APPLYING TO SKIN | THE GILLETTE COMPANY | 1996-05-07 | — | — | US | disclosed |
| EP-0467318-B1 | Fluorogenic tryptophanase substrates | BECTON DICKINSON CO (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0521871-A4 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0521871-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0467318-A1 | Fluorogenic tryptophanase substrates | Becton, Dickinson and Company (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5055594-A | Identifying microorganisms | BECTON, DICKINSON AND COMPANY (US) | 1991-10-08 | — | — | US | disclosed |
| WO-1991011988-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1991-08-22 | — | — | WO | disclosed |