Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 2/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014834 | 0.88 | TPMT (0.37) | TPMTTSHRNQO2IRAK4IKBKB | |
| SCHEMBL30539299 | 0.85 | TPMT (0.48) | TPMTTP53TSHRMAPK1MAOB | |
| SCHEMBL2010693 | 0.85 | TPMT (0.48) | TPMTTP53TSHRMAPK1MAOB | |
| SCHEMBL9009216 | 0.84 | TPMT (0.43) | TPMTTP53TSHRMAPK1MAOB | |
| Hydrochloric Acid SCHEMBL8516696 | 0.83 | TPMT (0.46) | TPMTTP53TSHRMAPK1MAOB | |
| Hydrochloric Acid SCHEMBL8379120 | 0.83 | TPMT (0.46) | TPMTTP53TSHRMAPK1MAOB | |
| SCHEMBL19693158 | 0.80 | TPMT (0.56) | TPMTTP53TSHRMAPK1 | |
| SCHEMBL28312637 | 0.76 | CFTR (0.43) | TPMTTSHRMAPK1NQO2 | |
| SCHEMBL23042699 | 0.75 | NQO2 (0.34) | TPMTTSHRNQO2IKBKB | |
| SCHEMBL1837458 | 0.75 | TPMT (0.37) | TPMTTSHRNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352788-A | ARTERIES | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1982-10-05 | — | — | US | disclosed |
| US-4348377-A | RADIOPACITY | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1982-09-07 | — | — | US | disclosed |