Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPRA | P18433 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | PTPRE | P23469 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539299 | 1.00 | TPMT (0.48) | TPMTTP53MAOBTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL8516696 | 0.98 | TPMT (0.46) | TPMTTP53MAOBTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL8379120 | 0.98 | TPMT (0.46) | TPMTTP53MAOBTSHRMAPK1 | |
| SCHEMBL19693158 | 0.85 | TPMT (0.56) | TPMTTP53TSHRMAPK1ALDH1A1 | |
| SCHEMBL9009216 | 0.85 | TPMT (0.43) | TPMTTP53MAOBTSHRMAPK1 | |
| SCHEMBL11295002 | 0.85 | TPMT (0.43) | TPMTTP53MAOBTSHRMAPK1 | |
| SCHEMBL31226172 | 0.82 | TPMT (0.48) | TPMTTP53MAOBTSHRMAPK1 | |
| SCHEMBL31534597 | 0.82 | TSHR (0.43) | TPMTTP53MAOBTSHRMAPK1 | |
| SCHEMBL3371190 | 0.81 | TPMT (0.52) | TPMTTP53MAOBTSHRALDH1A1 | |
| SCHEMBL28133536 | 0.81 | TPMT (0.43) | TPMTTP53TSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116421744-A | Absorbable medical hydrogel and preparation method thereof | 杭州融华再生医学科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| EP-3704177-A1 | RADIOPAQUE THERMOPLASTIC POLYMER | The Texas A&M University System (US) | 2020-09-09 | — | — | EP | claimed |
| EP-3548531-A1 | CHEMICALLY MODIFIED SHAPE MEMORY POLYMER EMBOLIC FOAMS WITH INCREASED X-RAY VISUALIZATION | The Texas A&M University System (US) | 2019-10-09 | — | — | EP | claimed |
| CN-106496058-B | The preparation method of non-ionic contrast agent Ioversol intermediate | 浙江海洲制药有限公司 | 2018-11-16 | — | — | CN | claimed |
| CN-106699594-B | A kind of preparation method of Iopromide | 山东诚汇双达药业有限公司 | 2018-11-06 | — | — | CN | claimed |
| WO-2018102779-A1 | CHEMICALLY MODIFIED SHAPE MEMORY POLYMER EMBOLIC FOAMS WITH INCREASED X-RAY VISUALIZATION | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-06-07 | — | — | WO | claimed |
| CN-106699594-A | Preparation method of iopromide | 山东诚汇双达药业有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-100560565-C | 5-amino-2,4, the synthetic method of 6-three triiodoisophthalic acid acyl chlorides | SHANXI XINTIANYUAN PHARMACEUTI (CN) | 2009-11-18 | — | — | CN | claimed |
| CN-101215244-A | Method for synthesizing 5-amino-2,4,6-triiodoisophthaloyl dichloride | SHANXI XINTIANYUAN PHARMACEUTI (CN) | 2008-07-09 | — | — | CN | claimed |
| CN-1721393-A | Process for preparing 5-acetamino-N,N'-bis (2,3-dihydroxypropyl)-2,4,6-tri-iodo isophthalamide | XINCHANG GUOBANG CHEMICAL INDU (CN) | 2006-01-18 | — | — | CN | claimed |
| EP-1113823-A2 | CHIRAL RADIO-CONTRAST AGENTS | Omnia Pharma S.R.L. (IT) | 2001-07-11 | — | — | EP | claimed |
| WO-2000015266-A2 | RADIO-CONTRAST AGENTS | OMNIA PHARMA S.R.L. (IT) | 2000-03-23 | — | — | WO | claimed |
| CN-221637361-U | Multifunctional distillate device | 四川仁安药业有限责任公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-116421744-B | Absorbable medical hydrogel and preparation method thereof | 杭州融华再生医学科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116688163-A | CT (computed tomography) developing hydrogel, and preparation method and application thereof | 领博生物科技(杭州)有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116421744-A | Absorbable medical hydrogel and preparation method thereof | 杭州融华再生医学科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| US-5488133-A | X-RAY CONTRAST AGENTS | EASTMAN KODAK COMPANY (US) | 1996-01-30 | — | — | US | disclosed |
| WO-1995024378-A1 | IODINATED AROYLOXY KETONES | NANOSYSTEMS, L.L.C. (US) | 1995-09-14 | — | — | WO | disclosed |
| US-4283381-A | OPAQUING AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-11 | — | — | US | disclosed |
| EP-0015867-A1 | Diamides of triiodo-isophthalic acids, their preparation and X-ray contrast agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-09-17 | — | — | EP | disclosed |