Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12690229 | 1.00 | MAPT (0.42) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL12690326 | 0.93 | MAPT (0.49) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL30440380 | 0.93 | MAPT (0.49) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL30887116 | 0.90 | MMP14 (0.47) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL13966044 | 0.86 | MAPT (0.39) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL17305940 | 0.81 | MAPK1 (0.36) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14822673 | 0.79 | MMP14 (0.44) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL13966035 | 0.79 | MAPT (0.45) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL29804181 | 0.77 | MAPT (0.47) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9345361 | 0.77 | MAPT (0.56) | MAPTRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056523-A2 | Aqueous dispersions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-07-28 | — | — | EP | disclosed |