MMP14 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL314001	0.82	16/20
SCHEMBL313984	0.70	16/20
SCHEMBL315578	0.65	16/20
SCHEMBL314397	0.79	14/20
SCHEMBL222143	0.73	14/20
SCHEMBL315716	1.00	13/20
SCHEMBL315035	0.77	13/20
SCHEMBL316169	0.77	13/20
SCHEMBL313884	0.51	13/20
SCHEMBL313379	0.47	13/20
SCHEMBL76378	1.00	12/20
SCHEMBL314064	1.00	12/20
SCHEMBL75828	0.92	12/20
SCHEMBL75459	0.92	12/20
SCHEMBL74593	0.78	12/20
SCHEMBL74232	0.77	12/20
SCHEMBL74255	0.77	12/20
SCHEMBL88026	0.77	12/20
SCHEMBL314725	0.74	12/20
SCHEMBL76108	0.71	12/20

Clinical trials — most relevant to MMP14 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Effect of Dipeptidyl Peptidase- 4 Inhibitors on Non-Alcoholic Steatohepatitis and Type 1 Diabetes	PHASE3	COMPLETED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
Synvisc to Treat Osteoarthritis of the Temporomandibular Joint	PHASE2	COMPLETED
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma	PHASE2	UNKNOWN
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
Salivary Markers in Periodontal Disorders	nan	COMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development	nan	COMPLETED
The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity	nan	WITHDRAWN
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus	nan	COMPLETED
Matrix Metalloproteinases 7 and 9 in Rheumatoid Arthritis Patients With Interstitial Lung Disease	nan	NOT_YET_RECRUITING
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9	nan	COMPLETED
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma	nan	COMPLETED
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation	nan	COMPLETED
Serum COMP and MMP-3 in Knee Osteoarthritis	nan	NOT_YET_RECRUITING
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED
Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia	nan	UNKNOWN
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Influence of Exercise Program on Serum Matrix Metalloproteinases and Functional Status in Women With Postmenopausal Osteoporosis	nan	COMPLETED
Prognostic Indices of Atheromatosis Severity and Coronary Artery Bypass Surgery Outcomes for Patients With Coronary Artery Disease	nan	ACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MMP14 binder may also engage these)

Protein	Name	Similarity
P53690	—	1.000	P53690 →
Q5RES1	—	1.000	Q5RES1 →
Q10739	—	1.000	Q10739 →
Q95220	—	1.000	Q95220 →
Q9GLE4	—	1.000	Q9GLE4 →
Q9XT90	—	1.000	Q9XT90 →
MMP24	Matrix metalloproteinase-24	1.000	landscape →
P57748	—	1.000	P57748 →
O54732	—	1.000	O54732 →
O18767	—	0.999	O18767 →
Q9WTR0	—	0.999	Q9WTR0 →
P50757	—	0.999	P50757 →
Q9GLE5	—	0.998	Q9GLE5 →
P41245	—	0.997	P41245 →
Q9EPL5	—	0.997	Q9EPL5 →
P07152	—	0.997	P07152 →
O55123	—	0.997	O55123 →
Q10835	—	0.997	Q10835 →
P52176	—	0.997	P52176 →
Q6Y4Q5	—	0.997	Q6Y4Q5 →
MMP3	Stromelysin-1	0.997	landscape →
MMP1	Interstitial collagenase	0.997	landscape →
Q3U435	—	0.996	Q3U435 →
P33434	—	0.996	P33434 →
MMP20	Matrix metalloproteinase-20	0.996	landscape →
MMP2	72 kDa type IV collagenase	0.996	landscape →
Q9R0S2	—	0.996	Q9R0S2 →
MMP15	Matrix metalloproteinase-15	0.996	landscape →
O88766	—	0.996	O88766 →
Q28397	—	0.995	Q28397 →