Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.41 |
| ▸ | MMP13 | P45452 | 8/20 | 0.41 |
| ▸ | MMP8 | P22894 | 7/20 | 0.41 |
| ▸ | MMP12 | P39900 | 7/20 | 0.41 |
| ▸ | MMP9 | P14780 | 6/20 | 0.41 |
| ▸ | MMP14 | P50281 | 6/20 | 0.41 |
| ▸ | MMP16 | P51512 | 6/20 | 0.41 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301045 | 1.00 | MMP2 (0.41) | MMP2MMP13MMP8MMP12MMP9 | |
| SCHEMBL11290722 | 0.95 | MMP2 (0.40) | MMP2MMP13MMP8MMP12MMP9 | |
| SCHEMBL11296544 | 0.93 | MMP2 (0.39) | MMP2MMP13MMP8MMP12MMP9 | |
| SCHEMBL11292236 | 0.93 | MMP2 (0.39) | MMP2MMP13MMP8MMP12MMP9 | |
| SCHEMBL11297370 | 0.92 | MMP2 (0.38) | MMP2MMP13MMP8MMP12MMP9 | |
| SCHEMBL11298354 | 0.91 | MMP2 (0.41) | MMP2MMP13MMP8MMP12MMP9 | |
| SCHEMBL11294506 | 0.91 | MMP2 (0.40) | MMP2MMP13MMP8MMP12MMP9 | |
| SCHEMBL11293162 | 0.91 | MMP2 (0.40) | MMP2MMP13MMP8MMP12MMP9 | |
| SCHEMBL11298821 | 0.90 | MMP2 (0.39) | MMP2MMP13MMP8MMP12MMP9 | |
| SCHEMBL11292555 | 0.89 | MMP2 (0.41) | MMP2MMP13MMP8MMP12MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | disclosed |