Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294526 | 0.96 | LMNA (0.49) | LMNAMAPTABCB11MAPK1POLB | |
| SCHEMBL11289940 | 0.95 | LMNA (0.57) | LMNAMAPTABCB11MAPK1POLB | |
| SCHEMBL11293789 | 0.92 | LMNA (0.52) | LMNAMAPTABCB11MAPK1POLB | |
| SCHEMBL11295533 | 0.91 | LMNA (0.48) | LMNAMAPTABCB11MAPK1POLB | |
| SCHEMBL11289971 | 0.89 | LMNA (0.58) | LMNAMAPTABCB11MAPK1POLB | |
| SCHEMBL11269898 | 0.89 | LMNA (0.56) | LMNAMAPTABCB11MAPK1POLB | |
| SCHEMBL11300097 | 0.88 | LMNA (0.49) | LMNAMAPTABCB11MAPK1POLB | |
| SCHEMBL11275748 | 0.88 | LMNA (0.58) | LMNAMAPTABCB11MAPK1POLB | |
| SCHEMBL11268263 | 0.88 | LMNA (0.58) | LMNAMAPTABCB11MAPK1POLB | |
| SCHEMBL11266263 | 0.88 | LMNA (0.58) | LMNAMAPTABCB11MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |