Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.86 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | CHAT | P28329 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389188 | 0.93 | — | — | |
| SCHEMBL15848 | 0.93 | — | — | |
| SCHEMBL678283 | 0.93 | ALDH1A1 (1.00) | ALDH1A1GSRDYRK2LMNATSHR | |
| SCHEMBL10626301 | 0.90 | ALDH1A1 (0.95) | ALDH1A1GSRDYRK2LMNATSHR | |
| Hydrogen Sulfide SCHEMBL29004370 | 0.90 | ALDH1A1 (0.95) | ALDH1A1GSRDYRK2LMNATSHR | |
| Ethylene Glycol SCHEMBL18339493 | 0.90 | ALDH1A1 (0.69) | ALDH1A1GSRDYRK2TRPA1NPC1 | |
| Ethane SCHEMBL20484119 | 0.88 | ALDH1A1 (0.90) | ALDH1A1GSRDYRK2LMNATSHR | |
| SCHEMBL28861335 | 0.86 | ALDH1A1 (0.86) | ALDH1A1GSRDYRK2LMNATSHR | |
| SCHEMBL23044768 | 0.84 | ALDH1A1 (0.82) | ALDH1A1GSRDYRK2LMNATSHR | |
| SCHEMBL29026718 | 0.84 | ALDH1A1 (0.82) | ALDH1A1GSRDYRK2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006205-B1 | PROCESS FOR THE PREPARATION OF CHLOROSTYRENECYCLOPROPANE CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0006205-A1 | Process for the preparation of chlorostyrenecyclopropane carboxylic acid derivatives | BAYER AG (DE) | 1980-01-09 | — | — | EP | disclosed |