Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | CBS | P35520 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938805 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 | |
| SCHEMBL17938809 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 | |
| SCHEMBL2464261 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 | |
| SCHEMBL17938765 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 | |
| SCHEMBL17938807 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 | |
| SCHEMBL2370035 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 | |
| SCHEMBL16535327 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 | |
| SCHEMBL11296037 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 | |
| SCHEMBL17938768 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 | |
| SCHEMBL17938820 | 1.00 | PTGS2 (0.48) | PTGS2LCKCBSCYP3A4TNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004753-B1 | PREPARATION OF TETRAHYDROBENZOXOCINS AND CIS-HEXAHYDRODIBENZOPYRANONES | ELI LILLY AND COMPANY (US) | 1982-05-26 | — | — | EP | disclosed |
| EP-0004753-A1 | Preparation of tetrahydrobenzoxocins and cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-17 | — | — | EP | disclosed |
| US-4171315-A | Preparation of cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
| US-4131614-A | Process for preparing cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1978-12-26 | — | — | US | disclosed |