Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438133 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2RAD52BAXMEN1KMT2A | |
| SCHEMBL151400 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2RAD52BAXMEN1KMT2A | |
| SCHEMBL8391173 | 0.84 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2AMAPTPOLB | |
| SCHEMBL9819626 | 0.84 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2AMAPTPOLB | |
| SCHEMBL16908299 | 0.80 | MAPT (0.64) | SMN1; SMN2RAD52BAXMEN1KMT2A | |
| SCHEMBL4400918 | 0.80 | MAPT (0.64) | SMN1; SMN2RAD52BAXMEN1KMT2A | |
| SCHEMBL1361161 | 0.80 | MAPT (0.64) | SMN1; SMN2RAD52BAXMEN1KMT2A | |
| SCHEMBL488808 | 0.79 | MEN1 (0.68) | SMN1; SMN2RAD52MEN1KMT2AMAPT | |
| SCHEMBL24319375 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2RAD52BAXMEN1KMT2A | |
| SCHEMBL2800007 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2RAD52BAXMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645605-A1 | NOVEL POLYAMINES, SYNTHESIS METHOD THEREOF AND USE THEREOF FOR THE SELECTIVE ELEMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING C02 | IFP Energies nouvelles (FR) | 2020-05-06 | — | — | EP | disclosed |
| US-4314807-A | CATIONIC POLYMER, ANIONIC SURFACTANT SHAMPOO | L'OREAL (FR) | 1982-02-09 | — | — | US | disclosed |