Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17934826 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2RAD52SLC18A3IDO1BAX | |
| SCHEMBL2800007 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2RAD52SLC18A3IDO1BAX | |
| SCHEMBL9060103 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2RAD52SLC18A3IDO1BAX | |
| SCHEMBL11438133 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2RAD52IDO1BAXMEN1 | |
| SCHEMBL19240286 | 0.85 | RAD52 (0.50) | SMN1; SMN2RAD52SLC18A3IDO1BAX | |
| SCHEMBL151400 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2RAD52IDO1BAXMEN1 | |
| SCHEMBL2801641 | 0.84 | KMT2A (0.52) | SMN1; SMN2SLC18A3MEN1KMT2AMAPT | |
| SCHEMBL2801591 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2RAD52IDO1BAXMEN1 | |
| SCHEMBL570899 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2RAD52IDO1BAXMEN1 | |
| Hydrochloric Acid SCHEMBL5485556 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2RAD52IDO1BAXMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047145-A1 | RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |