Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TYMP | P19971 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275366 | 0.83 | CA12 (0.44) | HPGDTSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL2743018 | 0.82 | HPGD (0.61) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL8862856 | 0.81 | GAA (0.60) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL7519591 | 0.81 | GAA (0.60) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL8862940 | 0.81 | GAA (0.60) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL8862746 | 0.81 | GAA (0.60) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL6013870 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL15894480 | 0.79 | HPGD (0.57) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL1463587 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL30274320 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753625-B1 | METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN ALPHA-OXYPHOSPHORUS GROUP BY USING AN ACTIVATOR | STRAITMARK HOLDING AG (CH) | 2017-08-02 | — | — | EP | disclosed |
| EP-2665734-B1 | METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN alpha-OXY PHOSPHORUS GROUP | STRAITMARK HOLDING AG (CH) | 2016-06-29 | — | — | EP | disclosed |
| EP-2665734-A1 | METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN alpha-OXY PHOSPHORUS GROUP | Straitmark Holding AG (CH) | 2013-11-27 | — | — | EP | disclosed |
| WO-2013034730-A2 | METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN ALPHA-OXYPHOSPHORUS GROUP BY USING AN ACTIVATOR | STRAITMARK HOLDING AG (CH) | 2013-03-14 | — | — | WO | disclosed |
| EP-2567961-A1 | Method for the manufacture of compounds containing an alpha-oxyphosphorus group by using an activator | Straitmark Holding AG (CH) | 2013-03-13 | — | — | EP | disclosed |
| WO-2012098255-A1 | METHOD FOR THE MANUFACTURE OF COMPOUNDS CONTAINING AN α-OXY PHOSPHORUS GROUP | STRAITMARK HOLDING AG (CH) | 2012-07-26 | — | — | WO | disclosed |