SCHEMBL11296801

SCHEMBL11296801

CCOc1cccc(C)c1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.51
GLA P06280 1/20 0.51
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
MRGPRX4 Q96LA9 1/20 0.48
TRPM4 Q8TD43 1/20 0.47
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
MAPT P10636 2/20 0.44
LMNA P02545 1/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
RXRG P48443 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1672245 0.89 CA12 (0.61) L3MBTL1GLACA12CA1CA2
SCHEMBL27051701 0.86 KMT2A (0.47) L3MBTL1CA12CA1CA2CA7
SCHEMBL2447016 0.85 L3MBTL1 (0.55) L3MBTL1GLACA12CA1CA2
SCHEMBL10339837 0.85 TP53 (0.50) TDP1TSHR
SCHEMBL23748674 0.83 PPARA (0.50) TDP1MAPTLMNAMEN1KMT2A
SCHEMBL31643476 0.83 PTPN1 (0.55) L3MBTL1CA12CA1CA2CA7
SCHEMBL9502979 0.82 MEN1 (0.52) TDP1ALDH1A1HPGDMAPTLMNA
SCHEMBL9504277 0.82 MEN1 (0.52) TDP1ALDH1A1HPGDMAPTLMNA
SCHEMBL22408082 0.82 L3MBTL1 (0.51) L3MBTL1GLACA12CA1CA2
SCHEMBL5464526 0.82 CA12 (0.55) L3MBTL1GLACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4276193-A MAGNESIUM DIHALIDE CARRIER, CATALYST COMPRISING AN ELECTRON DONOR, TITANIUM TETRACHLORIDE REDUCED WITH AN ORGANOALUMINUM HALIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-06-30 US claimed
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2025-07-24 US disclosed
CN-118451078-A Modified proteins and protein degrading agents 上海睿跃生物科技有限公司 2024-08-06 CN disclosed
US-12011444-B2 N-substituted indole derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-18 US disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
US-20240027903-A1 Resist Material And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
CN-116472292-A Modified proteins and protein degrading agents 上海睿跃生物科技有限公司 2023-07-21 CN disclosed
WO-2023061440-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2023-04-20 WO disclosed
EP-4157888-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS Cullgen (Shanghai), Inc. (CN) 2023-04-05 EP disclosed
US-20230057177-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2023-02-23 US disclosed
US-20230057177-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2023-02-23 US disclosed
US-20220175775-A1 N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2022-06-09 US disclosed
US-11241431-B2 N-substituted indole derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2022-02-08 US disclosed
WO-2021239117-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI) , INC. (CN) 2021-12-02 WO disclosed
US-20200289507-A1 N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2020-09-17 US disclosed
EP-0008764-B1 PROCESS FOR THE PREPARATION OF A CATALYST ON A SOLID CARRIER AND ITS USE IN THE POLYMERISATION OF PROPYLENE BAYER AG (DE) 1982-09-22 EP disclosed
US-4276193-A MAGNESIUM DIHALIDE CARRIER, CATALYST COMPRISING AN ELECTRON DONOR, TITANIUM TETRACHLORIDE REDUCED WITH AN ORGANOALUMINUM HALIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-06-30 US disclosed
EP-0008764-A2 Process for the preparation of a catalyst on a solid carrier and its use in the polymerisation of propylene BAYER AG (DE) 1980-03-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200289507-A1 N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS PTGER1, PTGER4, PTGER2 L3MBTL1 4704/4885GLA 3970/4885CA12 4750/4885
US-20220175775-A1 N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS PTGER1, PTGER4, PTGER2 L3MBTL1 4704/4885GLA 3970/4885CA12 4750/4885
US-12011444-B2 N-substituted indole derivatives as PGE2 receptor modulators PTGER1, PTGER4, PTGER2 L3MBTL1 4704/4885GLA 3970/4885CA12 4750/4885
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, MDM2 L3MBTL1 707/4885GLA 3308/4885CA12 4415/4885
US-20240027903-A1 Resist Material And Patterning Process LBR, HNRNPU, EWSR1 L3MBTL1 774/4885GLA 3643/4885CA12 2389/4885
US-11241431-B2 N-substituted indole derivatives as PGE2 receptor modulators PTGER1, PTGER4, PTGER2 L3MBTL1 4704/4885GLA 3970/4885CA12 4750/4885
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, TP53BP1 L3MBTL1 1176/4885GLA 2922/4885CA12 4484/4885
US-20230057177-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, MDM2 L3MBTL1 707/4885GLA 3308/4885CA12 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.