SCHEMBL11296831

SCHEMBL11296831

CC1CC(c2cccc(Cl)c2)c2c(Cl)cccc21

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 6/20 0.46
HTR2C P28335 6/20 0.46
HTR2B P41595 6/20 0.46
HRH3 Q9Y5N1 4/20 0.46
SLC6A3 Q01959 2/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
KDM1A O60341 1/20 0.38
RCOR1 Q9UKL0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11293012 0.83 HTR2A (0.56) HTR2AHTR2CHTR2BHRH3SLC6A3
SCHEMBL11291046 0.80 HTR2A (0.49) HTR2AHTR2CHTR2BHRH3SLC6A3
SCHEMBL11885856 0.70 DRD2 (0.51) HTR2AHTR2CHTR2BHRH3
SCHEMBL11885855 0.70 DRD2 (0.51) HTR2AHTR2CHTR2BHRH3
SCHEMBL11295269 0.70 HTR2A (0.46) HTR2AHTR2CHTR2BHRH3KDM1A
SCHEMBL11292597 0.69 HTR2C (0.46) HTR2AHTR2CHTR2BHRH3
SCHEMBL12875538 0.68 HTR2A (0.58) HTR2AHTR2CHTR2BHRH3SLC6A3
SCHEMBL31172459 0.68 HTR2A (0.58) HTR2AHTR2CHTR2BHRH3SLC6A3
SCHEMBL26822591 0.67 SLC6A2 (0.66) SLC6A3SLC6A2SLC6A4
SCHEMBL11129362 0.67 SLC6A2 (0.69) SLC6A3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0004591-B1 SHELL CATALYST, PROCESS FOR ITS PREPARATION AND ITS USE FOR THE PREPARATION OF ANTHRAQUINONES BASF Aktiengesellschaft (DE) 1982-03-31 EP disclosed
US-4255285-A FOR THE CATALYTIC OXIDATION OF A 1-PHENYLINDAN TO AN ANTHRAQUINONE; ATOMIZING AN AQUEOUS VANADIUM COMPOUND TO COAT AND ROAST MOVING CARRIER PARTICLES BASF AKTIENGESELLSCHAFT (DE) 1981-03-10 US disclosed
EP-0004591-A1 Shell catalyst, process for its preparation and its use for the preparation of anthraquinones BASF Aktiengesellschaft (DE) 1979-10-17 EP disclosed