Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16316966 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL18377814 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL4749397 | 0.78 | — | — | |
| SCHEMBL2931908 | 0.78 | APLNR (0.32) | — | |
| SCHEMBL2937834 | 0.78 | — | — | |
| SCHEMBL7963544 | 0.75 | ESR2 (0.32) | — | |
| SCHEMBL178339 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL19501864 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL18377811 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL18322605 | 0.72 | POLB (0.38) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511144-B2 | Reverse hydroxamic acid derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2009-03-31 | — | — | US | disclosed |
| US-7511144-B2 | Reverse hydroxamic acid derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2009-03-31 | — | — | US | disclosed |
| US-4281173-A | Preparation of unsaturated diesters by catalytic oxidative carbonylation of diolefins | ATLANTIC RICHFIELD COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4195184-A | Preparation of unsaturated monoesters by catalytic oxidative carbonylation of diolefins | ATLANTIC RICHFIELD COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4189599-A | Preparation of dimethyl adipate by the hydrogenation of dimethyl hex-3-endioate | ATLANTIC RICHFIELD COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4171450-A | Preparation of unsaturated diesters by catalytic oxidative carbonylation of diolefins | ATLANTIC RICHFIELD COMPANY (US) | 1979-10-16 | — | — | US | disclosed |