Cyclopentane

Cyclopentane

SCHEMBL11297129

C1CCCC1.NC(=S)SCc1ccccc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 6/20 0.59
NOS1 P29475 4/20 0.59
NOS3 P29474 1/20 0.59
NOS2 P35228 1/20 0.59
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
GAA P10253 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
SLC11A2 P49281 1/20 0.46
ALDH1A1 P00352 1/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1319633 0.94 IDO1 (0.65) IDO1NOS1NOS3NOS2CA12
SCHEMBL448067 0.92 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL22444393 0.92 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL28158653 0.92 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL23878380 0.92 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL23878381 0.92 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL22444385 0.92 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
Ammonia Solution, Strong SCHEMBL23878450 0.92 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
Methyl Alcohol SCHEMBL28258509 0.88 IDO1 (0.59) IDO1NOS1NOS3NOS2CA12
Butane SCHEMBL3696734 0.86 IDO1 (0.57) IDO1NOS1NOS3NOS2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4225682-A PEPTIZED DENKA CHEMICAL CORPORATION (US) 1980-09-30 US claimed
US-4250083-A A STYRENATED DIPHENYLAMINE PRESENT DURING EMULSION POLYMERIZATION FOLLOWED BY PEPTIZATION; STORAGE STABILITY DENKA CHEMICAL CORPORATION (US) 1981-02-10 US disclosed
US-4225682-A PEPTIZED DENKA CHEMICAL CORPORATION (US) 1980-09-30 US disclosed