SCHEMBL1319633

SCHEMBL1319633

NC(=S)SCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 6/20 0.65
NOS1 P29475 4/20 0.65
NOS3 P29474 1/20 0.65
NOS2 P35228 1/20 0.65
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA9 Q16790 1/20 0.61
TAAR1 Q96RJ0 2/20 0.52
GAA P10253 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
SLC11A2 P49281 1/20 0.50
CTSL P07711 1/20 0.45
CTSB P07858 1/20 0.45
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL23878450 0.98 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL22444385 0.98 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL22444393 0.98 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL23878380 0.98 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL28158653 0.98 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL23878381 0.98 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
SCHEMBL448067 0.98 IDO1 (0.63) IDO1NOS1NOS3NOS2CA12
Cyclopentane SCHEMBL11297129 0.94 IDO1 (0.59) IDO1NOS1NOS3NOS2CA12
Methyl Alcohol SCHEMBL28258509 0.94 IDO1 (0.59) IDO1NOS1NOS3NOS2CA12
Butane SCHEMBL3696734 0.92 IDO1 (0.57) IDO1NOS1NOS3NOS2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
CN-117736707-A 230 ℃ resistant high-salt resistant high-density water-based drilling fluid and preparation method and application thereof 中国石油大学(华东) 2024-03-22 CN claimed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP claimed
CN-115160513-B 240 ℃ high-temperature resistant high-salt resistant rigid-flexible blocking agent and preparation method thereof 中国石油大学(华东) 2023-08-01 CN claimed
CN-114605653-A Preparation method and application of biological thermoplastic elastomer replacing SBS 东南大学 2022-06-10 CN claimed
US-20090012199-A1 Photoinitiator anchored to silicate and use thereof to prepare polymer exfolidated silicate nanocomposite NATIONAL SCIENCE FOUNDATION 2009-01-08 US claimed
WO-2008000766-A2 POLYMERISATION FROM A DIALLYLAMINE AND A COMPOUND CONTAINING A MACROMOLECULAR CHAIN CONSISTING OF UNITS DERIVED FROM SUCH AN AMINE RHODIA OPERATIONS (FR) 2008-01-03 WO claimed
JP-2007517119-A 2007-06-28 JP claimed
US-20070145625-A1 Process for crosslinking free-radical crosslinkable polymers DOW GLOBAL TECHNOLOGIES INC. (US) 2007-06-28 US claimed
CN-1918236-A Free radical crosslinkable polymer: improved crosslinking process and composition DOW GLOBAL TECHNOLOGIES INC (US) 2007-02-21 CN claimed
EP-1699881-A2 FREE-RADICAL CROSSLINKABLE POLYMERS: IMPROVED PROCESS FOR CROSSLINKING AND COMPOSITIONS The Dow Global Technologies Inc. (US) 2006-09-13 EP claimed
WO-2006055372-A2 PHOTOINITIATOR ANCHORED TO SILICATE AND USE THEREOF TO PREPARE POLYMER EXFOLIATED SILICATE NANOCOMPOSITE CORNELL RESEARCH FOUNDATION, INC. (US) 2006-05-26 WO claimed
WO-2005066280-A2 FREE-RADICAL CROSSLINKABLE POLYMERS: IMPROVED PROCESS FOR CROSSLINKING AND COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-07-21 WO claimed
US-6265499-B1 POLYMERIZING MIXTURE MENICON CO., LTD. (JP) 2001-07-24 US claimed
US-3962304-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA IDO1 1074/4885NOS1 735/4885NOS3 743/4885
US-20090012199-A1 Photoinitiator anchored to silicate and use thereof to prepare polymer exfolidated silicate nanocomposite MSN, NAPA, SELE IDO1 3646/4885NOS1 1887/4885NOS3 2308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.