Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611481 | 0.81 | MEN1 (0.63) | MEN1KMT2ANPSR1TDP1LMNA | |
| SCHEMBL2340576 | 0.80 | MEN1 (0.61) | MEN1KMT2ANPSR1TDP1LMNA | |
| SCHEMBL10876641 | 0.78 | SMN1; SMN2 (0.52) | MEN1KMT2ATDP1SMN1; SMN2HSD17B10 | |
| SCHEMBL11297176 | 0.76 | KMT2A (0.67) | MEN1KMT2ANPSR1TDP1LMNA | |
| SCHEMBL1403606 | 0.75 | MEN1 (0.56) | MEN1KMT2ANPSR1TDP1LMNA | |
| SCHEMBL23098267 | 0.74 | HSD17B10 (0.56) | MEN1KMT2ATDP1LMNACYP1A2 | |
| SCHEMBL10926166 | 0.73 | NPC1 (0.59) | MEN1KMT2ANPSR1TDP1LMNA | |
| SCHEMBL10933206 | 0.73 | SMN1; SMN2 (0.50) | MEN1KMT2ANPSR1TDP1SMN1; SMN2 | |
| SCHEMBL11227392 | 0.73 | KMT2A (0.59) | MEN1KMT2ANPSR1TDP1LMNA | |
| SCHEMBL11374622 | 0.73 | CYP3A4 (0.59) | MEN1KMT2ANPSR1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279838-A | HYDROLYZING AN N-ACETYLAMINOARYL THIOPHOSPHATE OR PHOSPHATE | MITSUI TOATSU CHEMICALS INC. (JP) | 1981-07-21 | — | — | US | claimed |
| US-4279838-A | HYDROLYZING AN N-ACETYLAMINOARYL THIOPHOSPHATE OR PHOSPHATE | MITSUI TOATSU CHEMICALS INC. (JP) | 1981-07-21 | — | — | US | disclosed |