Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611481 | 0.83 | MEN1 (0.63) | KMT2AMEN1NPSR1TDP1LMNA | |
| SCHEMBL2340576 | 0.81 | MEN1 (0.61) | KMT2AMEN1NPSR1TDP1LMNA | |
| SCHEMBL18154535 | 0.81 | TSHR (0.54) | KMT2AMEN1NPSR1CA1CA2 | |
| SCHEMBL14808444 | 0.80 | KMT2A (1.00) | KMT2AMEN1NPSR1TDP1LMNA | |
| Diacetamate SCHEMBL863106 | 0.79 | KMT2A (0.81) | KMT2AMEN1NPSR1TDP1LMNA | |
| SCHEMBL6516221 | 0.78 | KMT2A (0.73) | KMT2AMEN1NPSR1TDP1LMNA | |
| SCHEMBL1403606 | 0.77 | MEN1 (0.56) | KMT2AMEN1NPSR1TDP1LMNA | |
| SCHEMBL18154533 | 0.77 | SMN1; SMN2 (0.55) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL861674 | 0.77 | SMN1; SMN2 (0.84) | KMT2AMEN1TDP1SMN1; SMN2HTT | |
| SCHEMBL171415 | 0.76 | SMN1; SMN2 (0.73) | KMT2AMEN1TDP1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113150029-B | Preparation method of thiophosphoric acid tri (4-aminophenyl) ester | 台州达辰药业有限公司 | 2022-03-18 | — | — | CN | claimed |
| US-4279838-A | HYDROLYZING AN N-ACETYLAMINOARYL THIOPHOSPHATE OR PHOSPHATE | MITSUI TOATSU CHEMICALS INC. (JP) | 1981-07-21 | — | — | US | claimed |
| CN-113150029-B | Preparation method of thiophosphoric acid tri (4-aminophenyl) ester | 台州达辰药业有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-113150029-A | Preparation method of thiophosphoric acid tri (4-aminophenyl) ester | 台州达辰药业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-4279838-A | HYDROLYZING AN N-ACETYLAMINOARYL THIOPHOSPHATE OR PHOSPHATE | MITSUI TOATSU CHEMICALS INC. (JP) | 1981-07-21 | — | — | US | disclosed |
| US-4256672-A | REACTING PHOSPHORUS OXYCHLORIDE OR PHOSPHORUS THIOCHLORIDE WITH AN AMINO-SUBSTUTUTED PHENOL COMPOUND | MITSUI TOATSU CHEMICALS, INC. (JP) | 1981-03-17 | — | — | US | disclosed |