Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770480 | 0.93 | RARB (0.56) | TAS2R14ARCA1CA2GSK3B | |
| SCHEMBL8578235 | 0.93 | RARB (0.53) | TAS2R14ARCA1CA2GSK3B | |
| SCHEMBL10817566 | 0.91 | RARB (0.57) | TAS2R14ARCA1CA2GSK3B | |
| SCHEMBL216706 | 0.88 | CA2 (0.64) | TAS2R14ARCA1CA2GSK3B | |
| SCHEMBL28170053 | 0.87 | MRGPRX4 (0.49) | TAS2R14ARCA1CA2GSK3B | |
| Ammonia Solution, Strong SCHEMBL22265084 | 0.86 | CA2 (0.61) | TAS2R14ARCA1CA2GSK3B | |
| SCHEMBL27765473 | 0.86 | CA2 (0.61) | TAS2R14ARCA1CA2GSK3B | |
| SCHEMBL28435413 | 0.86 | CA2 (0.61) | TAS2R14ARCA1CA2GSK3B | |
| SCHEMBL11453092 | 0.86 | CA2 (0.61) | TAS2R14ARCA1CA2GSK3B | |
| SCHEMBL15347438 | 0.86 | CA2 (0.61) | TAS2R14ARCA1CA2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57085881-A | — | — | None | — | — | JP | disclosed |
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| JP-S5785881-A | LIQUID CRYSTAL COMPOSITION | SEIKO EPSON CORP | 1982-05-28 | — | — | JP | disclosed |