SCHEMBL112973

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL113651	0.91	CXCR3 (0.51)	CXCR3KCNH2MAPTALDH1A1KDM4E
	SCHEMBL109940	0.89	CXCR3 (0.50)	CXCR3KCNH2MAPTTP53ALDH1A1
	SCHEMBL112669	0.84	CXCR3 (0.55)	CXCR3KCNH2MAPTTP53ALDH1A1
	SCHEMBL113280	0.84	CXCR3 (0.54)	CXCR3KCNH2MAPTTP53ALDH1A1
	SCHEMBL111883	0.83	CXCR3 (0.58)	CXCR3KCNH2MAPTTP53ALDH1A1
	SCHEMBL111828	0.82	CXCR3 (0.57)	CXCR3KCNH2MAPTALDH1A1KDM4E
	SCHEMBL113279	0.81	CXCR3 (0.51)	CXCR3KCNH2MAPTTP53ALDH1A1
	SCHEMBL110697	0.81	CXCR3 (0.51)	CXCR3KCNH2MAPTTP53ALDH1A1
	SCHEMBL111889	0.81	CXCR3 (0.67)	CXCR3KCNH2MAPTALDH1A1CYP1A2
	SCHEMBL112182	0.81	CXCR3 (0.57)	CXCR3KCNH2ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.