Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94431 | 0.86 | PTAFR (0.41) | PTAFRGAAALDH1A1RECQLCA1 | |
| SCHEMBL122260 | 0.68 | ADORA3 (0.46) | PTAFRGAAALDH1A1RECQLCA1 | |
| SCHEMBL5121302 | 0.68 | CA1 (0.66) | PTAFRCA1CA2CA4CA7 | |
| SCHEMBL28172958 | 0.68 | CA1 (0.49) | PTAFRGAAALDH1A1RECQLCA1 | |
| SCHEMBL29039568 | 0.68 | PTAFR (0.44) | PTAFRGAAALDH1A1RECQLCA1 | |
| Hydrochloric Acid SCHEMBL1697524 | 0.67 | CA1 (0.64) | PTAFRCA1CA2CA4CA7 | |
| SCHEMBL9636319 | 0.66 | GAA (0.44) | PTAFRGAAALDH1A1RECQLCA1 | |
| SCHEMBL10365364 | 0.66 | TOP2A (0.47) | PTAFRGAAALDH1A1RECQLCA1 | |
| SCHEMBL12562435 | 0.64 | GAA (0.47) | PTAFRGAAALDH1A1RECQLCA1 | |
| SCHEMBL8936614 | 0.64 | MEN1 (0.58) | PTAFRGAAALDH1A1RECQLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334070-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1982-06-08 | — | — | US | claimed |