SCHEMBL1129737

SCHEMBL1129737

C(=NN=Cc1ccccn1)c1ccccn1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.65
NPC1 O15118 7/20 0.64
RAB9A P51151 7/20 0.64
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
ATM Q13315 1/20 0.64
MAOA P21397 2/20 0.63
ALDH1A1 P00352 2/20 0.57
PKM P14618 1/20 0.57
USP2 O75604 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.53
LMNA P02545 2/20 0.53
G6PC1 P35575 1/20 0.52
MAOB P27338 1/20 0.50
MAPT P10636 2/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KDM4E B2RXH2 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10494065 1.00 NR4A1 (0.65) NR4A1NPC1RAB9AMEN1KMT2A
SCHEMBL9769011 0.87 NR4A1 (0.57) NR4A1NPC1RAB9AMEN1KMT2A
SCHEMBL28342420 0.82 NR4A1 (0.47) NR4A1NPC1RAB9AMEN1KMT2A
SCHEMBL28342419 0.82 NR4A1 (0.47) NR4A1NPC1RAB9AMEN1KMT2A
SCHEMBL103201 0.81
SCHEMBL103202 0.81
SCHEMBL7660041 0.81
SCHEMBL12807570 0.81
SCHEMBL12848695 0.81
SCHEMBL333460 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183326-B2 A living polymer endcapped with an azine compound; uniformly distributed reinforcing particulate fillers; tire treads with increased balance between rolling resistance and traction BRIDGESTONE CORPORATION (JP) 2012-05-22 US claimed
US-7879952-B2 Functionalized polymers BRIDGESTONE CORPORATION (JP) 2011-02-01 US claimed
US-20070149717-A1 Functionalized polymers BRIDGESTONE CORPORATION (JP) 2007-06-28 US claimed
WO-2006123343-A2 BIOLOGICALLY ACTIVE METAL-COATED PROTEINS RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-11-23 WO claimed
US-20230392065-A1 MONOVALENT BRINE-BASED RESERVOIR DRILLING FLUID SCHLUMBERGER TECHNOLOGY CORP (US) 2023-12-07 US disclosed
US-11767457-B2 Monovalent brine-based reservoir drilling fluid SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2023-09-26 US disclosed
US-10053526-B2 Catalyst for conjugated diene polymerization, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and compositions comprising foregoing UBE INDUSTRIES, LTD. (JP) 2018-08-21 US disclosed
US-20180201820-A1 Monovalent Brine-Based Reservoir Drilling Fluid SCHLUMBERGER TECHNOLOGY CORPORATION 2018-07-19 US disclosed
US-20170158786-A1 CATALYST FOR CONJUGATED DIENE POLYMERIZATION, CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, POLYBUTADIENE, AND COMPOSITIONS COMPRISING FOREGOING UBE INDUSTRIES, LTD. (JP) 2017-06-08 US disclosed
US-20170088763-A1 INTERNAL BREAKER COMPOSITIONS FOR WELLBORE APPLICATIONS M-I L.L.C. (US) 2017-03-30 US disclosed
WO-2017007978-A1 MONOVALENT BRINE-BASED RESERVOIR DRILLING FLUID SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2017-01-12 WO disclosed
US-20160152882-A1 CATALYTIC SYSTEM FOR BREAKER FLUID FORMULATIONS MI LLC (US) 2016-06-02 US disclosed
EP-0244603-A2 Polymers containing amino groups, their manufacture and their use BASF Aktiengesellschaft (DE) 1987-11-11 EP disclosed
EP-0052928-B1 WATER-BORNE SURFACE-COATING COMPOSITIONS CONTAINING COMPLEXED COBALT DRIERS Nuodex Inc. (US) 1984-04-11 EP disclosed
US-4389328-A Drier systems for water-borne surface-coating compositions NUODEX, INC. (US) 1983-06-21 US disclosed
EP-0052928-A1 Water-borne surface-coating compositions containing complexed cobalt driers Nuodex Inc. (US) 1982-06-02 EP disclosed
US-4311625-A Water-borne surface-coating compositions containing complexed cobalt driers TENNECO CHEMICALS, INC. (US) 1982-01-19 US disclosed
US-4230183-A CHELATE OF COBALT, NICKEL, IRON, CHROMIUM, OR COPPER TEXACO INC. (US) 1980-10-28 US disclosed
US-4230183-A CHELATE OF COBALT, NICKEL, IRON, CHROMIUM, OR COPPER TEXACO INC. (US) 1980-10-28 US disclosed
US-3965069-A Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst GENERAL ELECTRIC COMPANY (US) 1976-06-22 US disclosed