SCHEMBL333460

SCHEMBL333460

O/N=C/c1ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103201 1.00
SCHEMBL103202 1.00
SCHEMBL27962467 0.98 NR4A1 (0.59)
SCHEMBL30800889 0.98 NR4A1 (0.59)
Hydrochloric Acid SCHEMBL10825098 0.98 NR4A1 (0.59)
SCHEMBL29119568 0.98 NR4A1 (0.59)
SCHEMBL3889364 0.98 NR4A1 (0.59)
Hydrochloric Acid SCHEMBL28427030 0.98 NR4A1 (0.59)
Chloromethane SCHEMBL1169195 0.94 NR4A1 (0.55)
Iodomethane SCHEMBL366129 0.94 NR4A1 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279024-B A kind of xanthine oxidoreductase inhibitors and the preparation method and application thereof 华南理工大学 2018-09-14 CN claimed
CN-106279024-A A kind of xanthine oxidoreductase inhibitors and preparation method and application 华南理工大学 2017-01-04 CN claimed
US-6599370-B2 Stabilized alkaline compositions for cleaning microelectronic substrates MALLINCKRODT INC. 2003-07-29 US claimed
US-20250296933-A1 METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. 2025-09-25 US disclosed
EP-3768834-B1 NOVEL RNA-PROGRAMMABLE ENDONUCLEASE SYSTEMS AND USES THEREOF CRISPR THERAPEUTICS AG (CH) 2025-08-13 EP disclosed
US-12370263-B2 Cyclic dinucleotide derivative based antibody-drug conjugates DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-07-29 US disclosed
CN-119707962-A Aza four-membered ring connected pyrazolopyridine compound or pharmaceutically acceptable salt thereof and application thereof 中山大学 2025-03-28 CN disclosed
EP-4524154-A2 ANTIBODY-DRUG CONJUGATES OF CYCLIC DINUCLEOTIDE DERIVATIVES Daiichi Sankyo Company, Limited (JP) 2025-03-19 EP disclosed
EP-4139287-B1 SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION BAYER AG (DE) 2025-02-26 EP disclosed
WO-2025036467-A1 CIRCULAR RNA WITH INCREASED STABILITY AND EXPRESSION WUHAN UNIVERSITY (CN) 2025-02-20 WO disclosed
EP-3848054-B1 ANTIBODY-DRUG CONJUGATES OF CYCLIC DINUCLEOTIDE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2025-01-29 EP disclosed
WO-2002032919-A2 6-O-SUBSTITUTED ERYTHROMYCIN DERIVATIVES HAVING IMPROVED GASTROINTESTINAL TOLERANCE ABBOTT LABORATORIES (US) 2002-04-25 WO disclosed
US-6056939-A Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals BRACCO IMAGING S.P.A. (IT) 2000-05-02 US disclosed
US-5972959-A Oxime derivatives, their preparation and their therapeutic use SANKYO COMPANY, LIMITED (JP) 1999-10-26 US disclosed
EP-0708098-B1 Oxime derivatives, their preparation and their therapeutic use SANKYO CO (JP) 1999-03-03 EP disclosed
US-5780490-A A O-(2,4-OXA(OR THIA)ZOLIDINYL)PHENYLOXY(OR THIO OR AMINO) ALKYLOXIME; ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AND -HYPOGLYCEMIC AGENTS; LIVER, SKIN AND UROGENITAL DISORDERS SANKYO COMPANY, LIMITED (JP) 1998-07-14 US disclosed
US-5703096-A ANTIDIABETIC AGENTS; ALDOSE REDUCTASE INHIBITOR SANKYO COMPANY, LIMITED (JP) 1997-12-30 US disclosed
EP-0708098-A1 Oxime derivatives, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1996-04-24 EP disclosed
US-4950745-A Process for synthesis of oligonucleotides and compound for forming polymeric protecting group DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1990-08-21 US disclosed
US-3957805-A TREATMENT OF PAIN, MUSCLE SPASMS, ANXIETY, INFLAMMATION, OR TENSION AMERICAN CYANAMID COMPANY (US) 1976-05-18 US disclosed