Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.40 |
| ▸ | LAP3 | P28838 | 5/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298340 | 0.93 | ANPEP (0.36) | ANPEPLAP3ERAP1PDCD1LG2CD274 | |
| SCHEMBL11292280 | 0.85 | DPP4 (0.44) | ANPEPLAP3ERAP1DPP4DPP8 | |
| SCHEMBL18946364 | 0.83 | ANPEP (0.39) | ANPEPLAP3ERAP1ALDH1A1TDP1 | |
| SCHEMBL18919526 | 0.83 | ANPEP (0.39) | ANPEPLAP3ERAP1ALDH1A1TDP1 | |
| SCHEMBL11569050 | 0.83 | ANPEP (0.39) | ANPEPLAP3ERAP1ALDH1A1TDP1 | |
| SCHEMBL11569051 | 0.83 | ANPEP (0.39) | ANPEPLAP3ERAP1ALDH1A1TDP1 | |
| SCHEMBL1582293 | 0.83 | ANPEP (0.48) | ANPEPLAP3ERAP1MMP1MMP8 | |
| SCHEMBL11373398 | 0.81 | DPP8 (0.49) | ANPEPLAP3DPP4DPP8DPP9 | |
| SCHEMBL11288716 | 0.81 | DPP8 (0.49) | ANPEPLAP3DPP4DPP8DPP9 | |
| SCHEMBL11128452 | 0.80 | S1PR2 (0.37) | ANPEPLAP3ERAP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |