SCHEMBL1582293

SCHEMBL1582293

CC(C)C[C@H](N)C(=O)N[C@@H](C)P(=O)(O)O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 7/20 0.48
LAP3 P28838 6/20 0.48
ERAP1 Q9NZ08 1/20 0.48
SLC7A5 Q01650 1/20 0.45
LARS1 Q9P2J5 2/20 0.40
SCN9A Q15858 3/20 0.39
RNPEP Q9H4A4 2/20 0.39
DNPEP Q9ULA0 1/20 0.39
AAK1 Q2M2I8 1/20 0.38
MMP1 P03956 1/20 0.37
MMP8 P22894 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11292280 0.83 DPP4 (0.44) ANPEPLAP3ERAP1MMP1MMP8
SCHEMBL11297402 0.83 ANPEP (0.40) ANPEPLAP3ERAP1MMP1MMP8
SCHEMBL18919526 0.81 ANPEP (0.39) ANPEPLAP3ERAP1MMP1
SCHEMBL11569050 0.81 ANPEP (0.39) ANPEPLAP3ERAP1MMP1MMP8
SCHEMBL18946364 0.81 ANPEP (0.39) ANPEPLAP3ERAP1MMP1
SCHEMBL11569051 0.81 ANPEP (0.39) ANPEPLAP3ERAP1MMP1MMP8
SCHEMBL11288716 0.80 DPP8 (0.49) ANPEPLAP3
SCHEMBL11373398 0.80 DPP8 (0.49) ANPEPLAP3
SCHEMBL11128452 0.79 S1PR2 (0.37) ANPEPLAP3ERAP1MMP1MMP8
SCHEMBL1582512 0.78 FPR2 (0.42) ANPEPLAP3ERAP1SLC7A5LARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1325024-B1 SELECTIVE GROWTH MEDIA NEWCASTLE UPON TYNE HOSPITALS NAT HEALTH SERVICE TRUST (GB) 2011-04-20 EP disclosed
EP-1325024-A1 SELECTIVE GROWTH MEDIA The Newcastle upon Tyne Hospitals National Health Service Trust (GB) 2003-07-09 EP disclosed
WO-2002024725-A1 SELECTIVE GROWTH MEDIA NEWCASTLE UPON TYNE HOSPITALS NHS TRUST (GB) 2002-03-28 WO disclosed
US-4134972-A OLIGOPEPTIDES HOFFMANN-LA ROCHE INC. (US) 1979-01-16 US disclosed
US-4127649-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-11-28 US disclosed
US-4100275-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-07-11 US disclosed