Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.53 |
| ▸ | CTSG | P08311 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299000 | 0.94 | ELANE (0.54) | ELANECTSGALDH1A1MAPTHPGD | |
| Digiferruginol SCHEMBL30614617 | 0.89 | ELANE (0.69) | ELANECTSGALDH1A1MAPTHPGD | |
| Digiferruginol SCHEMBL23199057 | 0.89 | ELANE (0.69) | ELANECTSGALDH1A1MAPTHPGD | |
| SCHEMBL23486213 | 0.83 | ELANE (0.60) | ELANECTSGALDH1A1MAPTHPGD | |
| SCHEMBL16226244 | 0.82 | ELANE (0.76) | ELANECTSGALDH1A1MAPTMEN1 | |
| SCHEMBL11297243 | 0.82 | ELANE (0.51) | ELANECTSGALDH1A1MAPTHPGD | |
| SCHEMBL30146426 | 0.79 | ELANE (0.53) | ELANECTSGALDH1A1MAPTHPGD | |
| SCHEMBL16227013 | 0.77 | EGFR (0.57) | ELANECTSGALDH1A1MAPTHPGD | |
| SCHEMBL9629402 | 0.77 | ELANE (0.70) | ELANECTSGALDH1A1MAPTHPGD | |
| SCHEMBL11046061 | 0.77 | ELANE (0.80) | ELANECTSGALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052853-A1 | Bis-aminomethyl-anthraquinone derivatives, process for their manufacture, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-02 | — | — | EP | disclosed |