Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.70 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5919605 | 0.95 | ELANE (0.63) | ELANEGABRA1GABRB2CTSGKDM4E | |
| SCHEMBL30497048 | 0.90 | ELANE (0.67) | ELANEGABRA1GABRB2CTSGKDM4E | |
| SCHEMBL2834207 | 0.90 | ELANE (0.67) | ELANEGABRA1GABRB2CTSGKDM4E | |
| SCHEMBL16225888 | 0.84 | ELANE (1.00) | ELANEGABRA1GABRB2CTSGMEN1 | |
| SCHEMBL8425612 | 0.80 | ELANE (0.50) | ELANEGABRA1GABRB2CTSGKDM4E | |
| SCHEMBL11258271 | 0.79 | ELANE (0.49) | ELANEGABRA1GABRB2KDM4EMEN1 | |
| SCHEMBL11297406 | 0.77 | ELANE (0.53) | ELANECTSGKDM4EMEN1ALDH1A1 | |
| SCHEMBL15676646 | 0.76 | GABRA1 (0.64) | ELANEGABRA1GABRB2KDM4EMEN1 | |
| SCHEMBL11297243 | 0.76 | ELANE (0.51) | ELANECTSGKDM4EMEN1ALDH1A1 | |
| SCHEMBL30146426 | 0.73 | ELANE (0.53) | ELANECTSGKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314405-B1 | NEW COMPOUNDS OF THE ANTHRAQUINONE SERIES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1992-03-18 | — | — | EP | disclosed |
| EP-0314405-A1 | New compounds of the anthraquinone series | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1989-05-03 | — | — | EP | disclosed |