Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 2/20 | 0.49 |
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625150 | 0.86 | MAPT (0.62) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL2612577 | 0.86 | MAPT (0.56) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL11600205 | 0.83 | MAPT (0.59) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL21817077 | 0.82 | MAPT (0.58) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL11604892 | 0.81 | MAPT (0.55) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL10433548 | 0.81 | ADORA2A (0.53) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL9309236 | 0.80 | MAPT (0.51) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL11606051 | 0.78 | MAPT (0.51) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL595104 | 0.77 | P2RY12 (0.56) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL12769790 | 0.77 | NPC1 (0.49) | MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4265784-A | Azine liquid crystal compounds for use in light-control devices | GENERAL ELECTRIC COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4196975-A | Azine liquid crystal compounds for use in light-control devices | GENERAL ELECTRIC COMPANY (US) | 1980-04-08 | — | — | US | disclosed |