Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378620 | 0.94 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL2428620 | 0.91 | ALDH1A1 (0.51) | PTPN1ALDH1A1SYKTSHRSMN1; SMN2 | |
| SCHEMBL15474582 | 0.90 | ALDH1A1 (0.54) | ALDH1A1SYKTSHRSMN1; SMN2NPSR1 | |
| SCHEMBL11367106 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPK1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL13791083 | 0.83 | SYK (0.59) | PTPN1ALDH1A1SYKMAPK1L3MBTL1 | |
| SCHEMBL16295618 | 0.82 | KDM4E (0.50) | ALDH1A1TSHRKDM4E | |
| SCHEMBL20911525 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL15474743 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SYKL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL4224048 | 0.80 | DRD1 (0.63) | ALDH1A1TSHRSMN1; SMN2NPC1KDM4E | |
| SCHEMBL5755028 | 0.80 | KDM4E (0.71) | ALDH1A1TSHRACHENPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012098070-A1 | QUINOLINE DYRK1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-07-26 | — | — | WO | disclosed |