Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.63 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.47 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317193 | 1.00 | CETP (0.63) | CETPLPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL11489051 | 0.98 | CETP (0.61) | CETPLPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL1246418 | 0.93 | CETP (0.58) | CETP | |
| SCHEMBL11306425 | 0.86 | MEN1 (0.55) | CETP | |
| SCHEMBL21357931 | 0.85 | CETP (0.53) | CETPLPAR3LPAR1LPAR2 | |
| SCHEMBL21359778 | 0.85 | CETP (0.53) | CETPLPAR3LPAR1LPAR2 | |
| SCHEMBL27727354 | 0.81 | CA2 (0.51) | CETP | |
| SCHEMBL9300384 | 0.81 | CETP (0.49) | CETP | |
| SCHEMBL8487370 | 0.81 | CETP (0.49) | CETPLPAR3LPAR1LPAR2 | |
| SCHEMBL10778039 | 0.81 | CETP (0.68) | CETPLPAR3LPAR1LPAR2PLA2G2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100018-A1 | INHIBITORS OF AUTOTAXIN | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2012-07-26 | — | — | WO | claimed |