Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.58 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18583356 | 0.87 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2TRIM24TRIM33KMT2A | |
| SCHEMBL18917594 | 0.82 | GRIN2D (0.46) | ALDH1A1SMN1; SMN2TRIM24TRIM33KMT2A | |
| SCHEMBL4890466 | 0.82 | — | — | |
| SCHEMBL9653641 | 0.82 | — | — | |
| SCHEMBL4890469 | 0.82 | — | — | |
| SCHEMBL4253058 | 0.80 | CA1 (0.59) | ALDH1A1SMN1; SMN2TRIM24TRIM33KMT2A | |
| SCHEMBL4253063 | 0.80 | CA1 (0.59) | ALDH1A1SMN1; SMN2TRIM24TRIM33KMT2A | |
| SCHEMBL214209 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2TRIM24TRIM33KMT2A | |
| SCHEMBL214210 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2TRIM24TRIM33KMT2A | |
| SCHEMBL22925152 | 0.79 | HTT (0.60) | ALDH1A1SMN1; SMN2TRIM24TRIM33KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183326-B2 | A living polymer endcapped with an azine compound; uniformly distributed reinforcing particulate fillers; tire treads with increased balance between rolling resistance and traction | BRIDGESTONE CORPORATION (JP) | 2012-05-22 | — | — | US | claimed |
| US-7879952-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2011-02-01 | — | — | US | claimed |
| US-20070149717-A1 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2007-06-28 | — | — | US | claimed |
| US-8183326-B2 | A living polymer endcapped with an azine compound; uniformly distributed reinforcing particulate fillers; tire treads with increased balance between rolling resistance and traction | BRIDGESTONE CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| EP-2044129-B1 | VULCANIZATE COMPRISING AZINE FUNCTIONALIZED POLYMER | BRIDGESTONE CORP (JP) | 2011-02-16 | — | — | EP | disclosed |
| US-7879952-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2011-02-01 | — | — | US | disclosed |
| EP-2044129-A2 | FUNCTIONALIZED POLYMER | Bridgestone Corporation (JP) | 2009-04-08 | — | — | EP | disclosed |
| EP-1803740-B1 | Method for preparing functionalized polymers | BRIDGESTONE CORP (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-20080027171-A1 | A living polymer endcapped with an azine compound; uniformly distributed reinforcing particulate fillers; tire treads with increased balance between rolling resistance and traction | BRIDGESTONE CORPORATION | 2008-01-31 | — | — | US | disclosed |
| WO-2008013804-A2 | FUNCTIONALIZED POLYMER | BRIDGESTONE CORPORATION (JP) | 2008-01-31 | — | — | WO | disclosed |
| EP-1803740-A1 | Functionalized polymers | Bridgestone Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20070149717-A1 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2007-06-28 | — | — | US | disclosed |