SCHEMBL11297653

SCHEMBL11297653

O=C(Oc1ccc2cc(O)ccc2c1)c1ccc(O)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.61
ESR1 P03372 5/20 0.61
MEN1 O00255 8/20 0.61
MAPT P10636 3/20 0.61
TDP1 Q9NUW8 1/20 0.61
CASP3 P42574 2/20 0.60
SENP8 Q96LD8 2/20 0.60
SENP7 Q9BQF6 2/20 0.60
SENP6 Q9GZR1 2/20 0.60
ESR2 Q92731 3/20 0.55
NPC1 O15118 2/20 0.55
PKM P14618 1/20 0.55
HGFAC Q04756 2/20 0.49
TMPRSS2 O15393 1/20 0.49
MLNR O43193 1/20 0.49
ALDH1A1 P00352 1/20 0.49
F2 P00734 1/20 0.49
C1R P00736 1/20 0.49
F10 P00742 1/20 0.49
PLG P00747 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777824 0.96 KMT2A (0.65) KMT2AESR1MEN1MAPTTDP1
SCHEMBL8461218 0.93 KMT2A (0.58) KMT2AESR1MEN1MAPTTDP1
SCHEMBL23386312 0.93 KMT2A (0.66) KMT2AESR1MEN1MAPTTDP1
SCHEMBL8756308 0.93 KMT2A (0.61) KMT2AESR1MEN1MAPTTDP1
SCHEMBL12859553 0.93 KMT2A (0.66) KMT2AESR1MEN1MAPTTDP1
SCHEMBL8080214 0.91 KMT2A (0.66) KMT2AESR1MEN1MAPTTDP1
SCHEMBL8851038 0.89 KMT2A (0.77) KMT2AESR1MEN1MAPTTDP1
SCHEMBL1875366 0.89 KMT2A (0.77) KMT2AESR1MEN1MAPTTDP1
SCHEMBL768213 0.89 KMT2A (0.57) KMT2AESR1MEN1MAPTTDP1
SCHEMBL9793342 0.88 KMT2A (0.60) KMT2AESR1MEN1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0067618-A2 Wholly aromatic polyester capable of forming an anisotropic melt phase at an advantageously reduced temperature CELANESE CORPORATION (US) 1982-12-22 EP disclosed