SCHEMBL8080214

SCHEMBL8080214

O=C(Oc1ccc2cc(O)ccc2c1)c1cc(C(=O)Oc2ccc3cc(O)ccc3c2)cc(C(=O)Oc2ccc3cc(O)ccc3c2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.66
MEN1 O00255 8/20 0.66
ESR1 P03372 7/20 0.63
CASP3 P42574 2/20 0.61
SENP8 Q96LD8 2/20 0.61
SENP7 Q9BQF6 2/20 0.61
SENP6 Q9GZR1 2/20 0.61
NPC1 O15118 2/20 0.60
MAPT P10636 2/20 0.58
TDP1 Q9NUW8 1/20 0.58
ESR2 Q92731 5/20 0.56
PKM P14618 1/20 0.56
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
RAB9A P51151 1/20 0.44
CLK1 P49759 1/20 0.44
DYRK1A Q13627 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
NSD2 O96028 1/20 0.44
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11297653 0.91 KMT2A (0.61) KMT2AMEN1ESR1CASP3SENP8
SCHEMBL12859553 0.91 KMT2A (0.66) KMT2AMEN1ESR1CASP3SENP8
SCHEMBL23386312 0.91 KMT2A (0.66) KMT2AMEN1ESR1CASP3SENP8
SCHEMBL1875366 0.87 KMT2A (0.77) KMT2AMEN1ESR1CASP3SENP8
SCHEMBL8461218 0.87 KMT2A (0.58) KMT2AMEN1ESR1CASP3SENP8
SCHEMBL777824 0.86 KMT2A (0.65) KMT2AMEN1ESR1CASP3SENP8
SCHEMBL23386313 0.86 KMT2A (0.61) KMT2AMEN1ESR1CASP3SENP8
SCHEMBL777641 0.85 KMT2A (0.59) KMT2AMEN1ESR1CASP3SENP8
SCHEMBL9944054 0.84 KMT2A (0.59) KMT2AMEN1ESR1CASP3SENP8
Betanaphthol SCHEMBL16236859 0.84 KMT2A (0.84) KMT2AMEN1ESR1CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed