Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.57 |
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.45 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297455 | 0.87 | IDO1 (0.49) | CYP4F2CYP4A11FFAR1EPHX2HRH3 | |
| SCHEMBL11799007 | 0.86 | MAPT (0.59) | CYP4Z1MAPTSMN1; SMN2GAACA12 | |
| SCHEMBL11064964 | 0.84 | CYP4F2 (0.46) | CYP4F2CYP4A11CYP4Z1MITFMAPT | |
| SCHEMBL13159630 | 0.84 | CYP4F2 (0.66) | CYP4F2CYP4A11CYP4Z1MITFCYP4F11 | |
| SCHEMBL6774237 | 0.82 | NAMPT (0.42) | CYP4F2CYP4A11CYP4Z1MITFMAPT | |
| SCHEMBL11306238 | 0.81 | KLK7 (0.42) | CYP4F2CYP4A11CYP4Z1MITFFFAR1 | |
| SCHEMBL68902 | 0.80 | CYP4F2 (0.85) | CYP4F2CYP4A11CYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL6984766 | 0.80 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP4Z1MITFMAPT | |
| SCHEMBL11311288 | 0.80 | CYP4F2 (0.47) | CYP4F2CYP4A11CYP4Z1MITFCYP4F11 | |
| SCHEMBL6777451 | 0.79 | CYP4F2 (0.68) | CYP4F2CYP4A11CYP4Z1MITFCYP4F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281019-A | 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |