Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297690 | 0.87 | CYP4F2 (0.57) | EPHX2FFAR1CA12CA1CA2 | |
| SCHEMBL11302724 | 0.84 | CYP4F2 (0.51) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL15581506 | 0.84 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1HPGDTHRA | |
| SCHEMBL11306393 | 0.83 | FFAR1 (0.59) | FFAR1FFAR4 | |
| SCHEMBL11306238 | 0.82 | KLK7 (0.42) | IDO1EPHX2FFAR1CA12CA1 | |
| SCHEMBL2551765 | 0.81 | ALDH1A1 (0.50) | IDO1EPHX2CYP4F2CYP4A11ADRB2 | |
| SCHEMBL11306407 | 0.81 | GAA (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11299992 | 0.80 | CA12 (0.45) | FFAR1CA12CA1CA2CA9 | |
| SCHEMBL22922181 | 0.80 | CYP4F2 (0.59) | IDO1EPHX2CA12CA9CYP4F2 | |
| SCHEMBL14717782 | 0.79 | EPHX2 (0.56) | IDO1EPHX2FFAR1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281019-A | 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |