SCHEMBL1129773

SCHEMBL1129773

Cc1cc(C(C)(C)CC(C)(C)C)cc(C(=O)O)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HMGB1 P09429 1/20 0.53
▸ CXCL12 P48061 1/20 0.53
▸ SHBG P04278 1/20 0.42
▸ PHLPP2 Q6ZVD8 1/20 0.41
▸ ALDH1A1 P00352 5/20 0.41
▸ HSD17B10 Q99714 4/20 0.41
▸ HPGD P15428 3/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ CTH P32929 1/20 0.38
▸ CYP3A4 P08684 3/20 0.38
▸ CYP2C9 P11712 2/20 0.38
▸ HIF1A Q16665 2/20 0.38
▸ IDH1 O75874 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ AKR1C2 P52895 1/20 0.37
▸ AKR1C1 Q04828 1/20 0.37
▸ RXRB P28702 1/20 0.36
▸ KMT2A Q03164 3/20 0.36
▸ TDP1 Q9NUW8 2/20 0.36
▸ CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11758727 0.87 HSD17B10 (0.47) HMGB1CXCL12SHBGALDH1A1HSD17B10
SCHEMBL1129614 0.85 SHBG (0.41) HMGB1CXCL12SHBGALDH1A1HSD17B10
SCHEMBL30049162 0.85 SHBG (0.41) HMGB1CXCL12SHBGALDH1A1HSD17B10
SCHEMBL8081713 0.85 HMGB1 (0.54) HMGB1CXCL12PHLPP2ALDH1A1HSD17B10
SCHEMBL10582497 0.84 SHBG (0.40) HMGB1CXCL12SHBGALDH1A1HSD17B10
SCHEMBL9247513 0.84 AKR1C2 (0.51) SHBGALDH1A1HSD17B10HPGDKDM4E
SCHEMBL10519864 0.84 HSD17B10 (0.50) HMGB1CXCL12SHBGALDH1A1HSD17B10
SCHEMBL200257 0.82 SHBG (0.54) SHBGALDH1A1HSD17B10CYP3A4CYP2C9
SCHEMBL10463840 0.81 HIF1A (0.44) HMGB1CXCL12SHBGALDH1A1HSD17B10
SCHEMBL3807152 0.80 HMGB1 (0.56) HMGB1CXCL12PHLPP2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 — — US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 — — EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 — — US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 — — EP disclosed
EP-0338808-B1 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INT INC (US) 1995-08-23 — — EP disclosed
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 — — EP disclosed
EP-0542372-A1 2-Substituted saccharin derivative proteolytic enzyme inhibitors STERLING WINTHROP INC. (US) 1993-05-19 — — EP disclosed
US-5187143-A Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-02-16 — — US disclosed
EP-0262810-B1 SHEET RECORDING MATERIAL CONTAINING DYE-FORMING COMPONENTS Fuji Photo Film Co., Ltd. (JP) 1992-12-09 — — EP disclosed
EP-0482668-A1 Heat sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-04-29 — — EP disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 — — EP disclosed
US-4808566-A COLORLESS DYE IS DIMER OF 3-(4-SUBSTITUTED AMINOARYL)-3-(SUBSTITUTED INDOL-3-YL) PHTHALIDE FUJI PHOTO FILM CO., LTD. (JP) 1989-02-28 — — US disclosed
EP-0264751-A2 Hydroxycarboxylic acid derivatives and their application in copying materials BAYER AG (DE) 1988-04-27 — — EP disclosed
EP-0262810-A2 Sheet recording material containing dye-forming components Fuji Photo Film Co., Ltd. (JP) 1988-04-06 — — EP disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 — — EP disclosed
EP-0194518-A1 Reaction recording system BAYER AG (DE) 1986-09-17 — — EP disclosed
US-4257935-A CONTAINING AN ORGANIC COLOR DEVELOPER AND A POLYMERIC OLEFIN-CONJUGATED DIENE TYPE BINDER SUMITOMO NAUGATUCK CO., LTD. (JP) 1981-03-24 — — US disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 — — US disclosed
US-4125675-A Color developing sheet with organic developer and latex binder SUMITOMO NAUGATUCK CO., LTD. (JP) 1978-11-14 — — US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 — — US disclosed
Send feedback